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EVIDENCE-BASED HPB CARE

Research &
Publications

Generating evidence, advancing knowledge, and shaping the future of hepato-pancreato-biliary care in East Africa through rigorous clinical research and collaborative inquiry.

Our Focus

Research Focus Areas

Our research programme spans the full breadth of HPB disease, with particular emphasis on conditions and challenges unique to the East African context.

Hepatocellular Carcinoma in East Africa

Investigating the epidemiology, viral hepatitis-driven risk factors, and surgical outcomes of HCC in the region. Our studies aim to characterise presentation patterns, improve early detection strategies, and evaluate treatment efficacy in resource-variable settings.

Epidemiology Risk Factors Outcomes

Pancreatic Surgery Outcomes

Tracking and analysing Whipple procedure outcomes, post-operative morbidity, and long-term survival data. Our pancreatic surgery registry enables benchmarking against international standards and identification of modifiable factors to reduce perioperative mortality.

Whipple Outcomes Mortality Tracking Registry Data

Biliary Disease Patterns

Studying the prevalence and management of gallstone disease, cholangiocarcinoma, and iatrogenic bile duct injuries in the Tanzanian population. Research encompasses both open and laparoscopic approaches and aims to define best-practice pathways for the region.

Gallstone Disease Bile Duct Injuries Cholangiocarcinoma

Surgical Education Research

Evaluating training efficacy, simulation-based learning, and competency assessment in HPB surgery. Our education research informs curriculum design for fellowship programmes and measures the impact of structured training on surgical outcomes.

Training Efficacy Skills Assessment Simulation
Published Work

Recent Publications

A selection of our members' contributions to the global body of HPB literature.

Hepatocellular Carcinoma Presentation Patterns and Surgical Outcomes at a Tertiary Centre in Dar es Salaam

Mwanga A, Kahinga P, Lema B, et al.

HPB Journal · 2025 · View Publication

Perioperative Outcomes of Pancreaticoduodenectomy in Sub-Saharan Africa: A Multi-Centre Retrospective Analysis

Kahinga P, Mwanga A, Ngowi B, et al.

Annals of African Surgery · 2025 · View Publication

Bile Duct Injuries Following Laparoscopic Cholecystectomy in Tanzania: Incidence, Management, and Outcomes

Lema B, Mwanga A, Josephat S, et al.

East African Medical Journal · 2024 · View Publication

Simulation-Based Training in HPB Surgery: Impact on Operative Confidence Among East African Surgical Trainees

Ngowi B, Kahinga P, Mwanga A, et al.

Journal of Surgical Education · 2024 · View Publication

Multi-Disciplinary Tumor Board Impact on Treatment Decisions for Hepatobiliary Malignancies: A Prospective Study from Tanzania

Josephat S, Mwanga A, Lema B, et al.

World Journal of Surgery · 2024 · View Publication
Funding Opportunities

Research Grants & Funding

THPBA is committed to supporting HPB research in East Africa. We provide seed grants for pilot studies, facilitate access to international funding opportunities, and assist members in developing competitive grant applications.

THPBA Seed Grants

Annual competitive seed grants of up to $5,000 for members conducting original HPB research. Priority given to early-career investigators and projects addressing regional disease burden.

International Partnership Grants

Collaborative funding opportunities through our partnerships with IHPBA and international academic institutions, supporting multi-centre research with global impact.

Travel & Presentation Awards

Funding support for THPBA members to present original research at the IHPBA World Congress, E-AHPBA meetings, and other international surgical conferences.

Global Network

International Collaborations

Through strategic partnerships with leading institutions worldwide, we amplify the reach and impact of HPB research conducted in East Africa.

IHPBA

International Hepato-Pancreato-Biliary Association

As an IHPBA-affiliated national chapter, we participate in global registries, multi-centre trials, and benefit from research mentorship programmes connecting trainees with world leaders in HPB surgery.

University Partnerships

MUHAS, University of Cape Town, Johns Hopkins, Karolinska

Collaborative research agreements with leading universities enable joint study protocols, visiting researcher exchanges, shared biostatistics support, and co-authored publications in high-impact journals.

Regional Surgical Networks

COSECSA, E-AHPBA, East African HPB Consortium

Multi-national research collaborations across East and Southern Africa pool patient data, harmonise surgical protocols, and create the statistical power needed to generate evidence specific to the African context.

CALL FOR RESEARCH

Have a Research Idea?
We Want to Hear It.

THPBA welcomes research proposals from members at all career stages. Whether you are an established investigator or a surgical trainee with a compelling question, our Research Committee provides mentorship, methodological guidance, and institutional support to help bring your study to life.

Ethics committee support
Biostatistics mentorship
Manuscript preparation assistance